Efficient, Concise, and Chemoselective Synthesis of 1H‐Benzo[f]indole‐4,9‐dione with 4‐Hydroxycoumarin Substituent via a One‐Pot Three‐Component Reaction.

Autor: Alizadeh, Abdolali, Hasanpour, Hamidreza, Rezaiyehraad, Reza
Předmět:
Zdroj: ChemistrySelect; 12/22/2023, Vol. 8 Issue 48, p1-6, 6p
Abstrakt: Extensive studies on the biological activities of several quinone‐fused heterocycles have confirmed their outstanding antitumor activity. Therefore, a new family of 1H‐benzo[f]indole‐4,9‐dione derivatives with the 4‐hydroxycoumarin substitution was prepared by a high‐yield, one‐pot, concise three‐component reaction between arylglyoxals, 4‐hydroxycoumarin, and 2‐aminonaphthalene‐1,4‐dione derivatives under reflux in EtOH. This efficient protocol showed chemoselectivity in addition to facile operation procedure and easy purification. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index