| Autor: |
Piscopo, Leandra, Volpe, Fabio |
| Předmět: |
|
| Zdroj: |
European Journal of Nuclear Medicine & Molecular Imaging; Feb2024, Vol. 51 Issue 3, p800-802, 3p |
| Abstrakt: |
This article discusses the use of PET/CT imaging with radiolabeled FAPI as a new opportunity for the diagnosis and treatment of thyroid cancer. Differentiated thyroid cancer (DTC) is the most common endocrine neoplasm, and radioactive iodine (RAI) treatment is a mainstay therapy. However, some DTC patients become RAI-refractory, requiring alternative imaging modalities. PET/CT imaging with [18F]FDG is currently used, but it has limitations. New radiotracers, such as FAPI, have been proposed as potential markers of tumor burden. Studies have shown that [68Ga]Ga-DOTA.SA.FAPi PET/CT exhibits higher detection rates for certain metastases compared to [18F]FDG. The article suggests that a dual complementary approach may be necessary for the diagnosis, prognosis, and treatment of iodine-refractory DTC patients. Additionally, radiolabeled FAPI shows potential for theragnostic applications in aggressive variants of dedifferentiated thyroid cancer. [Extracted from the article] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
|
Nepřihlášeným uživatelům se plný text nezobrazuje |
K zobrazení výsledku je třeba se přihlásit.
|
