Nifedipine Induced Gingival Overgrowth - A Detailed Histopathological and Clinical Analysis: A Case Series.

Autor: Manjunatha, Vinayaka Ambujakshi, Wodeyar, Vibha Basavaraj, Pandey, Lakshmi, Machetty, Laxmi, G. V., Gayathri, M. G., Triveni
Předmět:
Zdroj: Oral & Maxillofacial Pathology Journal; Jul-Dec2023, Vol. 14 Issue 2, p233-237, 5p
Abstrakt: Introduction: Nifedipine is the drug used to treat angina pectoris and arrhythmia causing gingival hyperplasia. Withdrawal of nifedipine leads to the regression of overgrowth of gums and enhances the recovery rate. Case Presentation: Two patients treated with nifedipine were referred for assessment and management for their gingival overgrowth. Management and Prognosis: The patients were initiated with phase I therapy and a spectacular change was noticed after three months of drug replacement. There was retrogression in the magnitude of gingival tissue enlargement in both cases, with nominal fibrotic constituent, along with an improvement in the overall periodontal status. Conclusion: Drug induced gingival overgrowth can be treated initially with drug replacement followed by encouraging conscientious plaque controlling methods. Surgical intercession is undertaken if the overgrowth does not retrogress after drug replacement. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index