Sensors of Intracellular Nucleic Acids Activating STING-Dependent Production of Interferons in Immunocompetent Cells.

Autor: Smolyaninova, L. V., Solopova, O. N.
Zdroj: Biochemistry (Biokhimiya). Supplemental Series A, Membrane & Cell Biology; 2023 Suppl 1, Vol. 17, pS1-S19, 19p
Abstrakt: Currently, foreign DNA or RNA sensor proteins, which play an important role in innate immunity, are of great interest as a new avenue for cancer immunotherapy. This review considers the functioning of cytoplasmic nucleic acid sensors such as cGAS, STING, IFI16, AIM2, DAI, DDX41, DNA-PK, MRE-11, and TREX1, involved in activating the production of various cytokines. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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