COMPARITIVE STUDY OF MIDAZOLAM AND KETAMINE COMBINATION WITH XYLAZINE AND KETAMINE COMBINATION FOR CORNEAL LAMELLAR FLAP SURGERY IN RATS.

Autor: Kumar, Akshay, Singh, Kiranjeet, Gopinathan, Aswathy, SN, Chaithra, Arya, Manish, Sharma, Prabha, Alifsha
Předmět:
Zdroj: Journal of Experimental Zoology India; Jan2024, Vol. 27 Issue 1, p627-629, 3p
Abstrakt: When following the core principles of laboratory animal welfare, choosing an effective and appropriate anesthetic regimen for each individual animal is an essential part of laboratory animal testing. In order to control pain, anxiety and awareness during surgery and other operations, anesthesia is employed. Wistar rats of either sex and similar body weight totaled 60 in number, and they were randomly divided into two groups based on the types of anaesthetic utilized. For the induction of anesthesia, group A received an intraperitoneal combination of midazolam (5 mg/kg) and ketamine (50 mg/kg), and group B received an intraperitoneal combination of xylazine (5 mg/kg) and ketamine (50 mg/kg). It was discovered that both groups' anesthesia started at almost the same time. Group B having long recovery time from anesthesia than group A. The group A was found better than group B for the surgical procedure of less than 30 minutes. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index