Amiodarone-induced phlebitis: incidence and adherence to a clinical practice guideline.
| Autor: | Brørs, Gunhild, Gjeilo, Kari Hanne, Lund, Tonje, Skevik, Karin, Aa, Elizabeth, Høvik, Lise Husby, Skarsvaag, Torhild, Mjølstad, Ole Christian |
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| Předmět: |
FOREARM
RESEARCH INTRAVENOUS therapy ACADEMIC medical centers SCIENTIFIC observation PERIPHERALLY inserted central catheters PHLEBITIS MEDICAL protocols PRODUCT design PEARSON correlation (Statistics) T-test (Statistics) COMPARATIVE studies AMIODARONE RESEARCH funding QUESTIONNAIRES ELBOW DESCRIPTIVE statistics CHI-squared test DATA analysis software STATISTICAL correlation LONGITUDINAL method CENTRAL venous catheters SYMPTOMS |
| Zdroj: | European Journal of Cardiovascular Nursing; Nov2023, Vol. 22 Issue 8, p824-831, 8p |
| Abstrakt: | Aims: Intravenous amiodarone is an irritant of peripheral blood vessels with phlebitis as an adverse effect. The aims were to determine the incidence of intravenous amiodarone-induced phlebitis, to describe adherence to a clinical practice guideline, and to determine how characteristics were distributed between those with and without phlebitis. Methods and results: A prospective observational study was conducted. Adult patients treated with amiodarone through a peripheral intravenous catheter (PIVC) or a central venous catheter were included. PIVC characteristics were measured using the PIVC mini questionnaire. Patients with ≥two signs of phlebitis were categorized as having phlebitis. Adherence to the clinical practice guideline was registered on a standard abstract sheet. Data were collected from the amiodarone start-up to 2 days after the amiodarone was discontinued. In total, 124 patients with amiodarone infusions were observed, of which 69% were administered via a PIVC. The phlebitis rate was 44%. Fifty-three per cent developed amiodarone-induced phlebitis during the infusion phase, while 47% presented phlebitis during the post-infusion phase. The three most observed signs or symptoms of phlebitis were redness (87%), pain (81%), and swelling (71%). The most commonly used PIVC site was the elbow, and 35% of the PIVCs were large (18 gauge), which was the last preferred site and size according to the clinical practice guideline. Conclusion: A large proportion of the patients developed amiodarone-induced phlebitis. The adherence to the clinical practice guideline was not optimal according to the PIVC recommendations. Prevention of amiodarone-induced phlebitis should have high priority to reduce patient harm. Graphical Abstract [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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