| Abstrakt: |
A recent study conducted by researchers at Integral University in Uttar Pradesh, India, explored the impact of smoking tobacco on somatic mutations in mRNA genes and their potential role in lung cancer. The study found that the top five mRNA proto-oncogenes enriched with simple somatic mutations (SSM) in lung cancer cases due to tobacco consumption were TP53, EGFR, KRAS, FAT4, and KMT2D. Additionally, the researchers identified several microRNAs that bind specifically to these genes, suggesting the involvement of mRNA-miRNA interactions in the development of lung cancer. These findings provide valuable insights into the complex network of genetic alterations associated with lung cancer induced by smoking tobacco. [Extracted from the article] |
