Gastric Cancer: Correlation of Histologic Type with Commonly Used Prognostic Variables.

Autor: Taghavi, Afsoon, Khorsand, Atieh, Saberafsharian, Malihe, Sahabi, Reza, Beiraghdar, Mozhdeh, Hosseinpour, Mitra, Zahedifard, Sara, Fallah, Hadi Hajizadeh, Maghsoodi, Reza, Salarinejad, Sareh, Nasri, Parto, Eftekhari, Hamid Reza, Sadeghzadeh, Zahra, Hosseini, Masoumeh, Moradi, Arsham, Khasraghi, Leila Bahari
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Zdroj: International Journal of Cancer Management; Dec2023, Vol. 16 Issue 1, p1-7, 7p
Abstrakt: Background: Gastric cancer is one of the most common cancers among Iranian men and women. Objectives: The aim here was to investigate different histopathologic types and features of this cancer in association with selected prognostic variables. Methods: A retrospective cross-sectional study was performed to reevaluate the pathologic samples of 100 cases of gastric cancer referred to Shohadaye Tajrish Hospital, Tehran, Iran from 2017 to 2022. Results: We evaluated 100 cases of gastric cancer in this study. They had a mean age of 62.4 ± 13.44 years old (range 28 - 84 years) and were mostly men (n = 66,66 %). On histopathologic evaluation, tubular carcinoma was the most common type (n = 45,45%). We found a statistically significant correlation between the histologic type and perineural invasion (P-value = 0.024), lymphovascular invasion (P-value < 0.001), tumoral involvement of surgical margin (P-value = 0.012 ), infiltration depth of the primary tumor (pT) (P-value = 0.049), number of metastatic lymph nodes (pN) (P-value = < 0.001), tumor location in the antrum (P-value=0.033) and body (P-value = 0.013), and tumor size (P-value = 0.002 and P-value = 0.031 in small and large size groups respectively). Conclusions: According to the findings, histologic type of gastric cancer correlates with perineural invasion, lymphovascular invasion, tumoral involvement of the surgical margin, pT, pN, and tumor location and size. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index