| Abstrakt: |
Background: To assess cases of dengue infection using serology. Methods: A sum total of ninety-five cases of dengue virus infection in age 20-60 years of either gender was selected. All patients were subjected to evaluation of NS1 antigen, IgM and IgG antibodies. NS1 antigen and IgM antibodies using ELISA method and IgG antibodies were detected using lateral flow assay. Results: Out of 95 patients, males comprised 52 (54.7%) and females 43 (45.3%). Common clinical features recorded were arthralgia in 58%, myalgia in 42%, headache in 69%, retro-orbital pain in 31%, rash in 78% and bleeding in 56%. A significant difference between was observed (P<0.05). NS1 was identified in 48%, IgM in 22%, IgG in 5%, NS1+ IgM in 13%, NS1+ IgG in 4% and NS1+ IgM+ IgG in 8%. A significant difference was observed (P< 0.05). Conclusion: Male dengue infection rates were significantly higher than female rates. In the majority of cases, NS1 was found first, then NS1+ IgM. [ABSTRACT FROM AUTHOR] |
