Role of Clot Burden Score for Assessment of Right Ventricular Dysfunction in Patients with Acute Pulmonary Embolism.

Autor: Rathi, Bhavyansh, Agrawal, Juhi, Parihar, Bineeta Singh, Bagarhatta, Meenu, Mendiratta, Kuldeep, B., Ashwini
Předmět:
Zdroj: Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2023, Vol. 14 Issue 12, p1480-1490, 11p
Abstrakt: Background: Pulmonary embolism (PE) is a critical cardiovascular and pulmonary derangement and third most common cause of cardiovascular death. PE is a "great masquerader" because of non-specific presentation. In patients with suspected pulmonary embolism (PE) CT-pulmonary angiography (CTPA) is frequently performed and its relationship with Qanadli score (QS/clot burden score) assists the clinicians in early diagnosis and management. Our study highlights to determine the correlation between Q-score and parameters of right ventricular dysfunction (RVD) on CTPA in patients with acute pulmonary embolism. Materials and Methods: A prospective observational study done on 100 patients with radiologically confirmed diagnosis of PE in department of radiodiagnosis at SMS Medical College, Jaipur, rajasthan during one year period. Total of hundred (100) patients with radiologically confirmed diagnosis of PE were included whose clinical details, Q-score and RVD parameters [Right ventricle/left ventricle diameter (RV/LV) ratio, interventricular septum morphology, Superior vena cava (SVC) diameter, Azygos vein diameter, pulmonary artery/aorta diameter (PA/Ao) ratio and IVC reflux were recorded. Correlation between QScore and RVD parameters were determined, and logistic regression analysis was applied to assess Q-score as a predictor of RV-dysfunction. Results: A strong positive correlation was found between Q-score and RV/LV ratio, bowing of interventricular septum (r>0.7, p<0.05). Positive correlation between Q-score and PA/Ao ratio, SVC diameter, azygos vein diameter was also there after gender and age-based stratification. No significant correlation was found between Q-score and IVC reflux. ROC curve for QS showed a cut-off of 15 to precisely predict RVD. Conclusion: Qanadli score (QS) =15 correlates well with indicators of right ventricular dysfunction of CTPA in patients with acute pulmonary embolism and confers a poor prognosis with higher Q-scores. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index