Assessment of Effect of Coffee on Blood Pressure and Electrocardiographic Changes in Nicotine Users at a Tertiary Centre.

Autor: Kumar, Sunil, Arshad, Shazia Haque, Singh, Ajay Kumar, Kumari, Sarbil, Kumari, Neera
Předmět:
Zdroj: Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2023, Vol. 14 Issue 12, p174-178, 5p
Abstrakt: Background: Coffee is rich in antioxidants, which can help neutralise harmful free radicals in the body. Aims and Objectives: The present study was conducted to assess the effect of coffee on blood pressure and electrocardiographic changes in nicotine users. Materials and Methods: 80 subjects aged 21-45 years with a body mass index (BMI) between 17.3 and 28.0 kg/m² of both genders were divided into 2 groups of 40 each. Group I had the habit of smoking for more than 5 years, and Group II was healthy. An assessment of the electrocardiogram (ECG) and blood pressure was done. The computed standard lead-II ECG (CARDIART) was recorded three minutes before and forty-five minutes after coffee ingestion. Electrocardiographic measurements like QRS, RR, HR, QT, and QTc intervals of each ECG were automatically measured. Results: Group I had 25 males and 15 females, and Group II had 20 males and 20 females. Before and after coffee ingestion in groups I and II, the mean SBP (mmHg) was 121.4 and 132.2 in group I and 116.4 and 130.6 in group II. DBP (mmHg) was 74.6 and 76.2 in group I and 74.6 and 73.2 in group II. HR (bpm) was 80.4 and 74.2 in group I and 72.8 and 71.0 in group II. QRS (ms) was 86.5 and 89.2 in group I and 80.2 and 82.4 in group II. RR (ms) was 780.2 and 801.4 in group I and 854.2 and 836.4 in group II. QT (ms) was 360.6 and 372.4 in group I and 354.2 and 330.6 in group II. QTc (ms) was 416.4 and 418.2 in group I and 380.4 and 364.2 in group II. The difference was significant (P< 0.05). Conclusion: Caffeinated coffee does not acutely induce any significant change in the QTc interval duration in the subjects. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index