Innovative Technology of the Self-Emulsifying Drug Delivery System of the Anticonvulsant Galodif.

Autor:	Kuksenok, V. U., Shtrykova, V. V., Filimonov, V. D., Shushpanova, T. V., Bokhan, N. A., Seilerová, L., Kratohvil, B., Sieberová, V.
Předmět:	DRUG delivery systems TECHNOLOGICAL innovations DRUG solubility SCIENCE education CHEMICAL formulas REHABILITATION of people with alcoholism PHENOBARBITAL MICROEMULSIONS
Zdroj:	Russian Journal of Bioorganic Chemistry; 2023 Suppl1, Vol. 49, pS8-S12, 5p
Abstrakt:	This article explores the development of a self-emulsifying drug delivery system (SEDDS) to improve the solubility of the anticonvulsant drug Galodif in water. Galodif is currently limited in its therapeutic use due to its poor solubility. The study found that the SEDDS formulations significantly increased the solubility of Galodif in water compared to its tablet form. The use of SEDDS offers advantages such as increased bioavailability, faster onset of action, lower dosage, and reduced side effects. The ingredients used in the SEDDS are readily available, safe, and approved for use in pharmaceutical formulations. [Extracted from the article]
Databáze:	Complementary Index
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