| Autor: |
Yang Ruan, Chunguang Han, Dongmei Wang, Yuka Inoue, Amen, Yhiya, Othman, Ahmed, Yanisa Mittraphab, Maki Nagata, Kuniyoshi Shimizu |
| Předmět: |
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| Zdroj: |
Natural Product Research; 2023, Vol. 37 Issue 24, p4089-4098, 10p |
| Abstrakt: |
Four new natural compounds named hericenone O (1), hericenone P (2), hericenone Q (3), and hericenone R (4), two of them were reported synthetically (3-4), together with eleven known compounds were isolated from the fruiting bodies of Hericium erinaceus. The chemical structures of the isolated compounds were elucidated by using NMR analysis and mass spectrometry, as well as comparisons with the reported data in the literature. The bioactivity evaluation revealed that hericenone Q showed significant cytotoxic activity against Hep-G2 with IC50 values of 23.89 μM, and against HCT-116 with IC50 values of 65.64 μM. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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