| Autor: |
Pinheiro, Bethânia Camargo, Pinheiro, Tiago Novaes, Leite, Milena Gomes Melo, Garcia, Roberto Brandão, Bernardineli, Norberti, Faria, Flávio Duarte, Cintra, Luciano Tavares Angelo, Bramante, Clovis Monteiro |
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| Zdroj: |
Odontology; Jan2024, Vol. 112 Issue 1, p112-124, 13p |
| Abstrakt: |
To investigate the effect of ELVAX polymer subgingival implants incorporated with echistatin peptide on incisor reimplanted tooth in rats. Forty-two male Wistars rats were divided into two groups: echistatin-treated rats (E) and control rats (C). The animals had their right maxillary incisors extracted and treated according to the International Association of Dental Traumatology replantation protocol. The extra-alveolar dry period was 30 and 60 min, and the post-surgical experimental periods were 15, 60, and 90 days. The samples were stained with H&E and analyzed for the presence of an inflammatory response, incidence of resorptions, and dental ankylosis. Results were statistically analyzed (p < 0.05). The presence of inflammatory resorption was significantly higher in group C at 30 and 60 min extra-alveolar time, in the 15-day postoperative period as compared with the E group (p < 0.05). Dental ankylosis was significantly more prevalent in group E in 30 min extra-alveolar time and 15 days postoperative period (p < 0.05). However, in 60 min extra-alveolar time and 60 days postoperative period, dental ankylosis was more prevalent in C group (p < 0.05). The use of ELVAX subgingival implants with echistatin demonstrated therapeutic potential in preventing the experimental resorption process after replantation of maxillary incisors in rats. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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