| Autor: |
Jang, Hongjun, Kwak, Soo Yeon, Kim, Young Hoon, Han, Jae-hyuk, Park, Youngjik, Baek, Seung-Hoon, Lee, Dongjoo, Kim, Hyoungsu |
| Předmět: |
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| Zdroj: |
Synlett; Jan2024, Vol. 35 Issue 2, p221-224, 4p |
| Abstrakt: |
This article discusses the synthesis of N-{2-[4-(β-d-Glucopyranosyloxy)-2-methylphenyl]-1,1-dimethyl-2-oxoethyl}-3-methylthiophene-2-carboxamide (GPTC), a metabolite of the fungicide isofetamid. The authors describe the importance of certified reference materials (CRMs) for accurate analysis of toxic chemicals in food. They report a decagram-scale synthesis of GPTC to obtain a standard CRM for residue analysis in food. The synthesis involves several steps, including protection, amination, coupling, and glycosylation, resulting in the production of 25 grams of GPTC with a purity of 99.6%. The authors conclude that this synthetic approach can be used to establish a standard CRM for analyzing residues in food. [Extracted from the article] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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