| Autor: |
Streit, Fabian, Zillich, Lea, Frank, Josef, Kleineidam, Luca, Wagner, Michael, Baune, Bernhard T., Klinger-König, Johanna, Grabe, Hans J., Pabst, Alexander, Riedel-Heller, Steffi G., Schmiedek, Florian, Schmidt, Börge, Erhardt, Angelika, Deckert, Jürgen, Rietschel, Marcella, Berger, Klaus |
| Předmět: |
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| Zdroj: |
World Journal of Biological Psychiatry; Dec2023, Vol. 24 Issue 10, p865-880, 16p |
| Abstrakt: |
Objectives: The present study introduces the assessment of depression and depressive symptoms in the German National Cohort (NAKO), a population-based mega cohort. Distribution of core measures, and associations with sociodemographic factors are examined. Methods: The current analysis includes data from the first 101,667 participants (NAKO data freeze 100,000). Depression and depressive symptoms were assessed using a modified version of the depression section of the Mini-International Neuropsychiatric Interview (MINI), selfreported physician's diagnosis of depression, and the depression scale of the Patient Health Questionnaire (PHQ-9). Results: A lifetime physician's diagnosis of depression was reported by 15.0% of participants. Of those, 47.6% reported having received treatment for depression within the last 12months. Of the subset of 26,342 participants undergoing the full depression section of the modified MINI, 15.9% were classified by the MINI with a lifetime depressive episode. Based on the PHQ-9, 5.8% of the participants were classified as currently having a major or other depression by the diagnostic algorithm, and 7.8% according to the dimensional assessment (score ≥ 10). Increased frequency of depression measures and higher depression scores were observed in women and participants with lower education level or a family history of depression. Conclusions: The observed distributions of all depression measures and their associations with sociodemographic variables are consistent with the literature on depression. The NAKO represents a valuable epidemiologic resource to investigate depression, and the range of measures for lifetime and current depression allows users to select the most suitable instrument for their specific research question. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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