CDK7 and CDK9 inhibition interferes with transcription, translation, and stemness, and induces cytotoxicity in GBM irrespective of temozolomide sensitivity.

Autor: Bhutada, Isha, Khambati, Fatema, Cheng, Shi-Yuan, Tiek, Deanna M, Duckett, Derek, Lawrence, Harshani, Vogelbaum, Michael A, Mo, Qianxing, Chellappan, Srikumar P, Padmanabhan, Jaya
Zdroj: Neuro-Oncology; Jan2024, Vol. 26 Issue 1, p70-84, 15p
Databáze: Complementary Index