Prospects and challenges for graphene drums as sensors of individual bacteria.

Autor: Rosłoń, I. E., Japaridze, A., Naarden, L., Smeets, L., Dekker, C., van Belkum, A., Steeneken, P. G., Alijani, F.
Předmět:
Zdroj: Applied Physics Letters; Jan2024, Vol. 124 Issue 1, p1-9, 9p
Abstrakt: Graphene-drum-enabled nanomotion detection can play an important role in probing life at the nanoscale. By combining micro- and nanomechanical systems with optics, nanomotion sensors bridge the gap between mechanics and cellular biophysics. They have allowed investigation of processes involved in metabolism, growth, and structural organization of a large variety of microorganisms, ranging from yeasts to bacterial cells. Using graphene drums, these processes can now be resolved at the single-cell level. In this Perspective, we discuss the key achievements of nanomotion spectroscopy and peek forward into the prospects for application of this single-cell technology in clinical settings. Furthermore, we discuss the steps required for implementation and look into applications beyond microbial sensing. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index