| Autor: |
Liang, Wenjun, Kwan, Angela TH, Ye, Huifang, Mofatteh, Mohammad, Feng, Mingzhu, Wellington, Jack, Fu, Pingzhong, Wei, Wenlong, Sun, Yu, Huang, Jianhui, Luo, Jie, Chen, Yimin, Yang, Shuiquan, Zhou, Sijie |
| Předmět: |
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| Zdroj: |
Risk Management & Healthcare Policy; Dec2023, Vol. 16, p2757-2769, 13p |
| Abstrakt: |
Purpose: In this study, we aimed to determine whether post-Alberta Stroke Project Early CT Changes Score (post-ASPECTS) in anterior stroke and post-(posterior circulation) PC-ASPECTS in posterior stroke on CT can predict post-endovascular thrombectomy (EVT) functional outcomes among patients with acute ischemic stroke (AIS) after EVT.Patients and Methods: A total of 247 consecutive patients aged 18 and over receiving EVT for LVO-related AIS were recruited into a prospective database. The data was retrospectively analyzed between March 2019 and February 2022 from two comprehensive tertiary care stroke centers: Foshan Sanshui District People's Hospital and First People's Hospital of Foshan in China. Patient parameters included EVT within 24 hr of symptom onset, premorbid modified Rankin scale (mRS) ≤ 2, presence of distal and terminal cerebral blood vessel occlusion, and subsequent 24– 72-hr post-stroke onset CT scan. Univariate comparisons were performed using the Fisher's exact test or χ2 test for categorical variables and the Mann–Whitney U-test for continuous variables. Logistic regression analysis was performed to further analyze for adjusting for confounding factors. A p-value of ≤ 0.05 was statistically significant.Results: Overall, 236 individuals with 196 anterior circulation ischemic strokes and 40 posterior strokes of basilar artery occlusion were examined. Post-ASPECTS in anterior stroke and post-pc-ASPECTS as strong positive markers of favorable outcome at 90 days post-EVT; and lower rates of inpatient mortality/hospice discharge, 90-day mortality, and 90-day poor outcome were observed. Moreover, patients in the post-ASPECTS ≥ 7 cohort experienced shorter door-to-recanalization time (DRT), puncture-to-recanalization time (PRT), and last known normal-to-puncture time (LKNPT).Conclusion: Post-ASPECTS ≥ 7 in anterior circulation AIS and post-pc-ASPECTS ≥ 7 in posterior circulation can serve as strong prognostic markers of functional outcome after EVT. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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