New Findings in Alzheimer Disease Described from Brigham and Women's Hospital [Xenon gas (Xe) treatment to restore microglial functions in Alzheimer's disease (AD)].

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Zdroj: Pain & Central Nervous System Week; 1/8/2024, p707-707, 1p
Abstrakt: A recent study conducted at Brigham and Women's Hospital in Boston, Massachusetts, has found that Xenon gas treatment may be effective in restoring microglial functions in Alzheimer's disease (AD). Microglia, which play a role in the brain's immune system, have been implicated in the onset and progression of AD. The study showed that Xenon treatment can modulate the phenotype of microglia, increasing their phagocytic response and decreasing their proinflammatory signature. Additionally, Xenon treatment was found to reduce amyloid-beta plaque load in mouse and humanized AD models, suggesting that it could be a potential treatment for AD. [Extracted from the article]
Databáze: Complementary Index