Abstrakt: |
New research on prostate cancer conducted by Badji Mokhtar University in Annaba, Algeria, explores the association between certain genetic variations and the susceptibility to sporadic prostate cancer. The study analyzed six single nucleotide polymorphisms (SNPs) in the ghrelin (GHRL) and its receptor (GHSR) genes. The results showed no significant association between these genetic variations and prostate cancer, except for one GHSR genotype (rs2922126 TT), which was found to be more frequent in prostate cancer patients. The findings provide insights into the influence of GHRL and GHSR polymorphisms and gene-gene interactions in prostate cancer susceptibility, potentially guiding clinical decision-making and improving patients' quality of life. [Extracted from the article] |