Abstrakt: |
New research from the Federal University Espirito Santo in Alegre, Brazil, explores the leishmanicidal activity of alpha-bisabolol and its synthetic derivatives on the promastigotes and amastigotes forms of Leishmania infantum and L. amazonensis. The study found that alpha-bisabolol and its derivatives were effective in reducing the intracellular load of amastigote and inhibiting its ability to turn into promastigote again. The researchers suggest that these compounds could be potential options for developing new treatments against leishmaniasis, a public health problem in various regions. The research has been peer-reviewed and published in the journal Natural Product Research. [Extracted from the article] |