| Abstrakt: |
This article discusses a new method for synthesizing homoallylic diene halides, which are important compounds used in the preparation of the taxane A-ring system. Taxol, a compound with anticancer properties, has been synthesized using various methods, including a type II intramolecular Diels-Alder reaction. The authors of this article report a new synthesis method for homoallylic halides, which are important precursors for the taxane ring system. The synthesis of these compounds was achieved using readily available and inexpensive starting materials, and the reactions are potentially scalable for large-scale production. The article provides technical information about the synthesis and characterization of various chemical compounds, including data such as nuclear magnetic resonance (NMR) spectra, mass spectrometry (MS) results, and experimental procedures. The authors acknowledge Prof. Joaquín Tamariz for HRMS analysis, and supporting information for the article is available online. [Extracted from the article] |
