Spontaneous corneal perforation in treatment‐resistant MPO‐ANCA‐associated small vessel vasculitis.

Autor: Zehnder, Karin, Reinhold, Aja, Gugleta, Konstantin, Gatzioufas, Zisis
Předmět:
Zdroj: Acta Ophthalmologica (1755375X); 2022 Supplement 275, Vol. 100, pN.PAG-N.PAG, 1p
Abstrakt: Purpose: Spontaneous corneal perforation is a rare complication in peripheral ulcerative keratitis (PUK). Identifying the systemic cause of PUK is essential for optimal treatment. MPO‐ANCA‐associated small vessel vasculitis is a potential cause of PUK. Being an autoimmune disorder, immunosuppressive therapy is indicated. Besides steroids, biologicals such as rituximab can be used with excellent results. Methods: In this case report, we would like to present a 83‐year‐old male patient with PUK caused by MPO‐ANCA‐positive small vessel vasculitis. Results: In this patient with PUK due to small vessel vasculitis, a spontaneous corneal perforation could not be prevented despite maximal immunosuppressive therapy. Thus, a tectonic penetrating keratoplasty à chaud was inevitable. Conclusions: Ophthalmologists should be aware of the rare complication of corneal perforation secondary to PUK caused by vasculitis. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index