Autor: |
Desai, Niraj M., Leung, Sherry G., Motter, Jennifer D., Segev, Dorry L., Warren, Daniel, Durand, Christine M. |
Předmět: |
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Zdroj: |
Annals of Internal Medicine; Dec2023, Vol. 176 Issue 12, p1682-1684, 8p |
Abstrakt: |
A small uncontrolled trial conducted at Johns Hopkins investigated the safety and efficacy of a two-week direct-acting antiviral (DAA) prophylaxis for kidney transplantation from donors with hepatitis C virus (HCV) viremia to recipients without HCV viremia. The trial involved 10 kidney transplant recipients, and all 10 recipients had undetectable HCV RNA at the 12-week follow-up. One participant experienced transient liver function abnormalities, but there were no rejection events or deaths. The study suggests that a two-week DAA prophylaxis may be an effective and safe option for preventing HCV infection in kidney transplant recipients. [Extracted from the article] |
Databáze: |
Complementary Index |
Externí odkaz: |
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