Deep MALDI-MS Spatial Omics guided by Quantum Cascade Laser Mid-infrared Imaging Microscopy.

Předmět:	QUANTUM cascade lasers MID-infrared lasers MICROSCOPY ION mobility SPATIAL systems
Zdroj:	Medical Imaging Week; 1/6/2024, p136-136, 1p
Abstrakt:	This article discusses a preprint abstract that explores the use of quantum cascade laser mid-infrared imaging microscopy to guide mass spectrometry imaging in spatial omics. The goal is to improve the identification of molecules in complex biological systems and enable spatial biomarker discovery. The researchers demonstrate the effectiveness of this approach by identifying 120 sulfatides in arylsulfatase A-deficient mice. The article emphasizes the potential of this technique for studying structure-ion mobility relationships and improving ion mobility prediction algorithms. However, it is important to note that this preprint has not yet undergone peer review. [Extracted from the article]
Databáze:	Complementary Index
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