Abstrakt: |
A recent report from researchers at the University of Western Ontario in Canada provides new insights into intervertebral disc (IVD) degeneration, a major cause of back pain and disability. The study used mouse models to investigate the effects of anatomical location, strain, and sex on the progression of age-associated degeneration. The researchers found that there were marked differences in the presentation and progression of IVD degeneration based on anatomical region, sex, and strain. This information is important for researchers using mouse models to design and interpret experiments accurately. [Extracted from the article] |