| Abstrakt: |
A research report from Peking Union Medical College in Beijing, China discusses the role of extracellular vesicles (EVs) in promoting the migration and invasion of glioma cells. The study found that glioma human endothelial cells (GhECs) exhibit specific enrichment of MYO1C, a protein involved in cell invasion, in EVs. The researchers identified RAB31 as a key factor in the secretion of MYO1C into EVs, and found that knockdown of RAB31 reduced the enrichment of MYO1C in EVs, thereby attenuating the promotion of glioma cell invasion. This study provides new insights into the mechanisms underlying glioma cell invasion and suggests potential targets for therapeutic intervention. [Extracted from the article] |
