Acute toxicity test of ethanolic extract and n-hexane fraction of tiger milk (Lignosus rhinocerus sp.) against larva of artemia Salina L. using the brine shrimp lethality test (BSLT).

Autor:	Widyasari, Ratna, Sari, Dina Yuspita, Fadli, F.
Předmět:	ACUTE toxicity testing ARTEMIA ETHANOL PROBIT analysis LARVAE HEXANE MILK ALKALOIDS ISOQUINOLINE alkaloids
Zdroj:	AIP Conference Proceedings; 2023, Vol. 2913 Issue 1, p1-5, 5p
Abstrakt:	Tiger milk mushroom (Lignosus rhinocerus sp.) contains secondary metabolites, namely flavonoids and alkaloids which at certain levels could be toxic and have antimicrobial and anti-inflammatory activities. This study aims to determine the cytotoxic activity of ethanol extract and n-hexane fraction of tiger milk mushroom (Lignosus rhinocerus sp.) using the BSLT (Brine Shrimp Lethality Test) method. The characteristics of the ethanolic extract are greenish brown and the n-hexane fraction are brown with a special scent. This research was conducted using 48 hours of Artemia salina Leach larvae. The LC50 value was calculated using probit analysis. The results showed that the ethanol extract and n-hexane fraction of tiger milk mushroom (Lignosus rhinocerus sp.) had cytotoxic activity against Artemia salina Leach. with LC50 values of 446.68 ppm and 812.83 ppm. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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