| Autor: |
Hizli, Şamil, Dereci, Selim, Özdemir, Özdemir, Duran, Fatih, Hidimoğlu, Burcu, Mazman, Duygu İskender, Gülhan, Belgin, Acar, Banu Çelikel |
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| Zdroj: |
Pediatrics International; Jan-Dec2023, Vol. 65 Issue 1, p1-7, 7p |
| Abstrakt: |
Background: Multisystem inflammatory syndrome in children (MIS‐C) is hyperinflammation following coronavirus disease 2019 (COVID‐19), which affects many organs. The retina and choroid are affected by COVID‐19 through microangiopathy and thrombosis but the literature on MISC‐C is limited. Methods: Thirty children (60 eyes) with MIS‐C (the study group, or SG) and 32 age‐and gender‐matched healthy children (64 eyes) (the control group, or CG) were included in the prospective case–control study. Complete ophthalmological examinations, measurements of the vessel densities of the retinal layers, and flow area of the outer retina and choriocapillaris in both groups were conducted with optical coherence tomography angiography (OCT‐A). Results: The mean age of the SG was 11.9 ± 3.9 and that of the CG was 12.5 ± 4.6 years (p = 0.197). In this study we found that the vessel density of the deep layer of the inner retina was decreased significantly and was reduced in the outer retina of flow area in the SG in comparison with the CG (p < 0.05, for all). However, there was no significant difference between the groups regarding other measurements. Conclusions: In MIS‐C patients, vessel densities in the deep layer of the inner retina and in the flow area of the outer retina decreased significantly. This OCTA‐A finding suggests that MIS‐C is related to endothelial thrombotic condition problems in small branches of the retinal artery. The results of this study support the idea that there is a need for screening of MIS‐C patients for the presence of these microangiopathic and perfusional complications. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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