Impact of Tobacco Use on 30-Day Mortality in Subjects Presenting with Spontaneous Intracerebral Hematoma: Retrospective Analysis of 335 Subjects.
| Autor: | Gülensoy, Esen Sayın, Gülensoy, Bülent |
|---|---|
| Předmět: |
INTENSIVE care units
HEMATOMA CEREBRAL hemorrhage CONFIDENCE intervals NON-smokers MULTIPLE regression analysis RETROSPECTIVE studies ACQUISITION of data MANN Whitney U Test FISHER exact test REGRESSION analysis RISK assessment T-test (Statistics) COMPARATIVE studies MEDICAL records GLASGOW Coma Scale SYMPTOMS DESCRIPTIVE statistics SMOKING ODDS ratio DATA analysis software LOGISTIC regression analysis STATISTICAL models |
| Zdroj: | Lokman Hekim Health Sciences; 2023, Vol. 3 Issue 2, p132-139, 8p |
| Abstrakt: | Introduction: Spontaneous intracerebral hematoma (ICH) causes significant morbidity and mortality. Risk factors for early mortality still need to be clearly elucidated. This study aimed to identify factors associated with 30-day mortality, hematoma volume, and the presence of intravascular hematoma in subjects presenting with spontaneous ICH. Methods: All consecutive subjects (>18 years) admitted to the intensive care unit between January 2013 and June 2021 with spontaneous ICH were analyzed retrospectively. Detailed systemic and neurological examinations were recorded and evaluated from files. Results: A total of 335 subjects (51.3% male, median age 68 [55-77] years) with ICH were included in the study. Of these, 230 were smokers (68.7%), 105 were nonsmokers (31.3%). Compared to nonsmokers, smokers had a lower Glasgow Coma Scale score (p=0.036), larger hematoma volume (p=0.034), higher frequency of intraventricular hematoma (p=0.013). Multiple logistic regression revealed that smokers had 2.069-fold higher risk of death than nonsmokers (OR: 2.069, 95% CI: 1.115-3.839, p=0.021). Smoking was also independently associated with the presence of intraventricular hematoma (OR: 1.669, 95% CI: 1.027-2.711, p=0.039). Discussion and Conclusion: The study showed that smokers have a 2.069-fold greater risk of 30-day mortality and a 1.669-fold higher likelihood of having intraventricular hematoma following spontaneous ICH than nonsmokers. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
| Externí odkaz: |
|