| Autor: |
Oikarinen, Lasse, Paavola, Mika, Montonen, Juha, Viitasalo, Matti, Mäkijärvi, Markku, Toivonen, Lauri, Katilat, Toivo |
| Předmět: |
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| Zdroj: |
Pacing & Clinical Electrophysiology; Oct1998, Vol. 21 Issue 10, p1934-1942, 9p |
| Abstrakt: |
QT dispersion is a measure of heterogeneity in ventricular repolarization. Increased ECG QT dispersion is associated with life-threatening ventricular arrhythmias. We studied if magnetocardiographic (MCG) measures of QT dispersion can separate postmyocardial infarction patients with and without susceptibility to sustained VT. Manual dispersion measurements were compared to a newly adopted automatic QT interval analysis method. Ten patients with a history of sustained VT (VT group) and eight patients without ventricular arrhythmias (Controls) were studied after a remote myocardial infarction. Single-channel MCGs were recorded from 42 locations over the frontal chest area and the signals were averaged. QT dispersion was defined as maximum - minimum or standard deviation of measured QT intervals. VT group showed significantly more QT and JT dispersion than Controls. QTapex dispersions were 127 ± 26 versus 83 ± 21 ms (P = 0.004) and QTend dispersions 130 ± 37 versus 82 ± 37 ms (P = 0.013), respectively. Automatic method gave comparable values. Their relative differences were 9% for QTapex and 27% for QTend dispersion on average. In conclusion, increased MCG QT interval dispersion seems to be associated with a susceptibility to VT in postmyocardial infarction patients. MCG mapping with automated QT interval analysis may provide a user independent method to detect nonhomogeneity in ventricular repolarization. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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