| Abstrakt: |
A study conducted at the University of Ghent in Belgium aimed to evaluate the association between plasma protein-bound uremic toxins (PBUTs) concentrations, echocardiographic parameters of heart failure (HF), and incident HF events in patients with chronic kidney disease (CKD) not on dialysis. The study included 523 patients with CKD stages G1-G5, and levels of certain PBUTs were measured. The results showed that elevated free concentrations of certain PBUTs were independently associated with an increased risk of HF events in non-dialyzed CKD patients. Further research is needed to confirm these findings and explore potential interventions to lower PBUTs and reduce the risk of HF events in this patient group. [Extracted from the article] |
