| Abstrakt: |
A recent study conducted in Sao Carlos, Brazil, explored the effects of anti-inflammatory treatments on supravalvular aortic stenosis (AS), a condition associated with heart failure. The study used an experimental model of heart failure induced by AS in rats and evaluated the effects of dexamethasone (DEX) and ramipril treatment on inflammation and cardiac fibrosis. The results showed that both treatments were effective in reducing cardiac inflammation, but only DEX attenuated the increased relative wall thickness, while only ramipril reduced left ventricle (LV) fibrosis. The study suggests that anti-inflammatory treatments could potentially delay the poor prognosis associated with heart failure. [Extracted from the article] |
