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| Zdroj: |
Pain & Central Nervous System Week; 12/29/2023, p675-675, 1p |
| Abstrakt: |
A study conducted by researchers at St. Mary's College of Maryland explores the role of the tumor suppressor gene, phosphatase and tensin homolog deleted on chromosome 10 (Pten), in regulating adult neurogenesis in the brain. The study found that the conditional deletion of Pten in mice leads to increased cell proliferation and immature neuroblasts in the dentate gyrus of the hippocampus. The researchers also observed region-specific increases in apoptotic cells in certain areas of the dentate gyrus. This study contributes to our understanding of the negative regulatory role of Pten in adult neurogenesis and provides insights into the temporal and spatial aspects of this process. [Extracted from the article] |
| Databáze: |
Complementary Index |
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