High-Dose Inhaled Nitric Oxide in Acute Hypoxemic Respiratory Failure due to COVID-19: A Multicenter Phase 2 Trial.

Autor: Di Fenza, Raffaele, Shetty, Naman S., Gianni, Stefano, Parcha, Vibhu, Giammatteo, Valentina, Fakhr, Bijan Safaee, Tornberg, Daniel, Wall, Olof, Harbut, Piotr, Lai, Peggy S., Li, Jonathan Z., Paganoni, Sabrina, Cenci, Stefano, Mueller, Ariel L., Houle, Timothy T., Akeju, Oluwaseun, Bittner, Edward A., Bose, Somnath, Scott, Louie K., Carroll, Ryan W.
Zdroj: American Journal of Respiratory & Critical Care Medicine; 12/15/2023, Vol. 208 Issue 12, pE1-E68, 68p
Abstrakt: The article focuses on a multicenter phase 2 trial investigating the use of high-dose inhaled nitric oxide in the treatment of acute hypoxemic respiratory failure due to COVID-19. Topics discussed include the study design, participant criteria, randomization and masking procedures, and the primary and secondary outcomes analyzed using Bayesian estimation.
Databáze: Complementary Index