Autor: |
Dong, Na, Liu, Shuda, Li, Yuye, Meng, Shuyun, Liu, Yifan, Li, Xia, Liu, Dong, You, Tianyan |
Předmět: |
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Zdroj: |
Chemical Communications; 1/14/2024, Vol. 60 Issue 1, p110-113, 4p |
Abstrakt: |
Here, we develop an all-in-one strategy for efficient assembly of an electrochemical aptasensor. A multifunctional structure based on a tetrahedral DNA nanostructure (TDN) was synthesized via a one-step annealing process, providing DNA fixation, target recognition, signal amplification and space regulation. Based on the integration of this multifunctional structure, the sensing interface was assembled in one step. A ratiometric aptasensor was constructed by anchoring methylene blue (MB) to the TDN and ferrocene (Fc) on the cDNA. Using the ratio of the currents obtained from Fc and MB as a measure, the developed aptasensor shows excellent analytical performance for fumonisin B1 detection. This strategy is universal and could simplify the fabrication of aptasensors. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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