The Inhibitory Activity of Lactobacillus plantarum Supernatant against Enterobacteria, Campylobacter, and Tumor Cells.

Autor:	Danilova, T. A., Adzhieva, A. A., Mezentseva, M. V., Suetina, I. A., Danilina, G. A., Minko, A. G., Dmitrieva, M. L., Zhukhovitsky, V. G.
Předmět:	ENTEROBACTERIACEAE CAMPYLOBACTER INHIBITION (Chemistry) ESCHERICHIA coli SHIGELLA flexneri LACTOBACILLUS plantarum CAMPYLOBACTER jejuni
Zdroj:	Bulletin of Experimental Biology & Medicine; Nov2023, Vol. 176 Issue 1, p64-67, 4p
Abstrakt:	Cell-free supernatant of Lactobacillus plantarum exhibit a strong antimicrobial effect against a number of pathogenic enterobacteria (E. coli, Shigella flexneri, Salmonella typhimurium, Proteus mirabilis, and Campylobacter jejuni). The degree of growth inhibition in broth culture reached a high level for all tested bacteria. The highest rates were noted for P. mirabilis (by 13 times) and the lowest for S. flexneri (by 5 times) and C. jejuni (by 4.5 times). Significant antiproliferative effect of the supernatant on cells of tumor-derived epithelial cell lines was shown. The highest degree of inhibition (by 22 times) was observed for HT-29 cells (colon carcinoma). Thus, inclusion of probiotics in traditional treatment schemes can increase the effectiveness of antibacterial and antitumor drug therapy. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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