Reports from Suez Canal University Highlight Recent Research in Diabetic Retinopathy (Protective Effect of Topiramate against Diabetic Retinopathy and Computational Approach Recognizing the Role of NLRP3/IL-1b/TNF-a Signaling).

Předmět:
Zdroj: Diabetes Week; 12/18/2023, p183-183, 1p
Abstrakt: A recent study conducted by researchers at Suez Canal University in Ismailia, Egypt, explores the potential protective effect of topiramate against diabetic retinopathy (DREN) and its molecular mechanisms. The study utilized a computational approach and found that mice treated with topiramate showed improvements in retinal pathologies, decreased levels of certain inflammatory markers, and enhanced expression of brain-derived neurotrophic factor (BDNF). These findings suggest that topiramate may have neuroprotective properties for DREN, although further research is needed to fully understand its mechanism of action. The study was published in the journal Biomedicines. [Extracted from the article]
Databáze: Complementary Index