| Abstrakt: |
A study conducted at the University of California Los Angeles (UCLA) examined the outcomes of epilepsy surgery for patients with hemimegalencephaly (HME), a rare congenital brain malformation that often leads to drug-resistant epilepsy. The study included 56 patients who underwent different surgical interventions, including anatomic hemispherectomy (AH), functional hemispherectomy (FH), and less-than-hemispheric resection (LTH). The results showed that initial AH may provide greater odds of seizure freedom compared to FH, with comparable complications and functional outcomes. The study also identified factors such as younger age at seizure onset, absence of epilepsia partialis continua (EPC), and no contralateral seizures on electroencephalography (EEG) that predicted longer postoperative seizure freedom. This research provides valuable information for physicians and parents of children undergoing surgery for HME. [Extracted from the article] |
