Study Findings from Affiliated Hospital of Guangdong Medical University Update Knowledge in Alzheimer Disease (Microglial TLR4/NLRP3 Inflammasome Signaling in Alzheimer's Disease).

Předmět:	ALZHEIMER'S disease INFLAMMASOMES MICROGLIA CENTRAL nervous system diseases TOLL-like receptors
Zdroj:	Genomics & Genetics Weekly; 12/22/2023, p2346-2346, 1p
Abstrakt:	A new report from the Affiliated Hospital of Guangdong Medical University in Zhanjiang, China, discusses the role of microglial TLR4/NLRP3 inflammasome signaling in Alzheimer's disease (AD). The study highlights the molecular complexity of AD and the importance of neuroinflammation in its pathology. The researchers explore the interplay between Toll-like receptor 4 (TLR4) and the NLRP3 inflammasomes in microglia and their influence on AD pathology. The review also discusses the potential of targeting these molecules as a treatment option for AD. [Extracted from the article]
Databáze:	Complementary Index
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