Epithelioid Angiomyolipoma with Tumor Thrombus into Inferior Vena Cava Presurgically Treated with Combination Therapy of Pembrolizumab and Axitinib: A Case Report.

Autor: Kawasoe, Chihiro, Miyamoto, Yoshi, Ito, Kaoru, Murashima, Takaya, Nagai, Takahiro, Takamori, Hiroki, Kiwaki, Takumi, Kamimura, Toshio, Mukai, Shoichiro, Kamoto, Toshiyuki
Předmět:
Zdroj: Research & Reports in Urology; Oct2023, Vol. 15, p447-452, 6p
Abstrakt: Epithelioid angiomyolipoma (EAML) is a rare variant of AML with malignant potential. It is occasionally difficult to distinguish EAML from renal cell carcinoma (RCC) on imaging. A 72-year-old woman was admitted to our hospital for the treatment of a left renal tumor with relatively high blood flow and a tumor thrombus extending to the inferior vena cava, suggesting RCC. The patient underwent presurgical combination therapy with axitinib and pembrolizumab. This treatment significantly shortened the thrombus, and radical nephrectomy was performed. The pathological findings were compatible with EAML, and the treatment effects were observed. We report a case treated pre-surgically with a combined therapy of pembrolizumab and axitinib, with a favorable response as a treatment option for EAML. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index