| Autor: |
RAJPUT, ROHAN, SINGHAL, SAURABH, HORA, ADARSH, MOURYA, SUDHIR |
| Předmět: |
|
| Zdroj: |
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2023, Vol. 14 Issue 11, p360-372, 13p |
| Abstrakt: |
Background: Renal involvement is one of the dreaded consequences of chronic liver disease associated with high mortality and morbidity. The cause of this renal dysfunction is either multi-organ involvement in acute conditions or secondary to advanced liver disease. The present study aimed to assess the incidence and causal relationship of various factors for different types of renal failure in cirrhotic patients. Material & Method: After approval from the IEC this prospective cross-sectional study was undertaken in Department of General Medicine, IMCHRC, Indore. 100 patients admitted with chronic liver disease were included after considering the inclusion criteria. Patients were clinically examined and laboratory investigations to diagnose the aetiology of chronic liver disease, and assess the severity of liver and renal dysfunction were done. Results: M:F ratio of 4.5:1 (mean age 44.68yrs). 70% patients had alcoholic liver disease, followed by 20% which had hepatorenal syndrome, 12% patients who had chronic Hepatitis-B, 10% patients developed acute kidney injury and 14% had IgA deposition. A statistically significant distribution was observed for serum urea and creatinine across the categories of Child Pugh classification. Conclusion: Renal impairment in patients with advanced liver disease is a common finding, more commonly associated with a more advanced disease. Presence of PHTN and various signs of decompensation increase the chances of renal derangements in these patients. This study emphasizes the fact that we should be more vigilant when treating CLD patients, regarding their renal function, as proper screening, prevention and treatment of renal dysfunction can decrease morbidity and mortality. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
