| Autor: |
Lynch, Kathleen D., Brian, Garry, Ahwang, Tomisina, Morotti, Wendy, Wharton, Ghislaine, Newie, Tomi, Newie, Victoria, Perrett, Christine, Ware, Wagie, Mosby, Lucy, Walters, Shelley, Brown, Anthony, Whop, Lisa J., Lambert, Stephen B. |
| Předmět: |
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| Zdroj: |
Ophthalmic Epidemiology; Dec2023, Vol. 30 Issue 6, p663-670, 8p |
| Abstrakt: |
We undertook a screening program between 2016 and 2019 to determine if trachoma was endemic in the Torres Strait Islands of Queensland, Australia. Eleven screening surveys assessing trachoma prevalence were undertaken in seven communities using the World Health Organization (WHO) simplified grading tool. Additionally, an ophthalmologist performed a detailed clinical assessment including examination for Herbert's pits and corneal pannus and, where clinically indicated, collection of conjunctival specimens to investigate the presence of Chlamydia trachomatis nucleic acid. Prevalence of trachomatous inflammation—follicular (TF) in children aged 5–9 years for the aggregated first survey across all communities was 6% (17/284). No child had trachomatous inflammation—intense, trachomatous scarring, corneal pannus, or Herbert's pits. Of the 66 times any child was tested for C. trachomatis by polymerase chain reaction (PCR), the result was negative. No cicatricial trachoma was identified amongst the adults (n = 186) who were opportunistically offered examination. Whilst TF was present, the lack of intense inflammatory thickening in any child examined, the lack of end-stage trachomatous disease, and the lack of ocular C. trachomatis detection by PCR indicate trachoma is not endemic in the Torres Strait Islands, and no ongoing public health intervention is required. These findings add to a growing body of evidence suggesting that use of the WHO simplified grading tool alone in the peri-elimination setting may overestimate the community burden of trachoma. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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