THE INFLUENCE OF METAL IONS ON GLUCOSE FORMATION BY THE LIVER.

Autor: Fantl, P., Rome, M. Noël
Zdroj: Australian Journal of Experimental Biology & Medical Science; Mar1944, Vol. 22 Issue 1, p45-50, 6p, 1 Diagram, 2 Charts, 5 Graphs
Abstrakt: Magnesium ions, in a concentration similar to that found in the normal liver, exert a regulatory effect on phosphorylase in extracts of rabbits' livers. In contrast to the effect with muscle phosphorylase, manganese or zinc ions cause an inhibition of polysaccharide breakdown in liver between pH 6 to 7. With neither metal is the inhibition abolished by the addition of magnesium or glycine, but whereas manganese causes an irreversible inactivation of liver phosphorylase, the inhibitory effect of zinc may be overcome by cysteine. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index