A sustainable approach towards the three-component Yb(OTf)3 and taurinecatalyzed synthesis of bioactive 2-phenyl-1H-imidazole and pyrimido[4,5-b]quinoline.

Autor: Nipate, Amol S., Jadhav, Chetan K., Chate, Asha V., Gill, Charansingh. H.
Předmět:
Zdroj: Chemistry & Biology Interface; Sep/Oct2023, Vol. 13 Issue 5, p123-137, 15p
Abstrakt: An efficient, convenient and environmentally benign one-pot three-component reaction for the synthesis of 2-phenyl-1H-imidazoleandpyrimido[4,5-b]quinoline derivatives as pharmacologically active compound. Yb(OTf)3 and 2-aminoethanesulfonic acid in water an environmentally friendly catalyst and green solvent, is still highly desirable. Advantages of these protocols such as simple work-up procedure, short reaction times, excellent yields, and the use of nontoxic and inexpensive catalysts. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index