Abstrakt: |
A recent study conducted by researchers from the Department of Gynecology explores the relationship between vaginal microecological changes, oncogene E6/E7 expression, and high-risk human papillomavirus (HR-HPV) infection. The study involved 1327 women who underwent HPV screening, vaginal microecology determination, and cytological testing. The findings suggest that bacterial vaginosis (BV) and E6/E7 mRNA expression are independent risk factors for HR-HPV infection, and HR-HPV infection increases the risk of cervical cancer. The study provides insights into the potential use of E6/E7 mRNA detection as a diagnostic tool for HR-HPV infection and highlights the importance of restoring vaginal microecological balance in the prevention and control of cervical cancer. [Extracted from the article] |