Abstrakt: |
A study conducted by investigators at the University of Tubingen in Germany has found that Staphylococcus aureus, a type of Gram-positive bacteria, uses wall teichoic acid (WTA) to attach to endothelial cells in blood vessels. The researchers discovered that the oxidized low-density lipoprotein receptor 1 (LOX-1) on endothelial cells interacts with S. aureus WTA, facilitating the binding of the bacteria to human endothelial cells. The study suggests that blocking LOX-1 could potentially prevent or treat severe endovascular infections caused by S. aureus. This research has been peer-reviewed and published in ACS Infectious Diseases. [Extracted from the article] |