Oral and Topical Administration of a Standardized Saw Palmetto Oil Reduces Hair Fall and Improves the Hair Growth in Androgenetic Alopecia Subjects – A 16-Week Randomized, Placebo-Controlled Study.

Autor:	Sudeep, Heggar Venkataramana, Rashmi, Sriram, Jestin, Thomas V, Richards, Aleksander, Gouthamchandra, Kuluvar, Shyamprasad, Kodimule
Předmět:	ORAL drug administration HAIR growth TOPICAL drug administration HAIR HAIR transplantation BALDNESS
Zdroj:	Clinical, Cosmetic & Investigational Dermatology; Nov2023, Vol. 16, p3251-3266, 16p
Abstrakt:	Objective evaluation was performed using the global photographic assessment score. Hair density, thickness, and anagen/telogen ratio were evaluated using phototrichogram analysis.Results: At the end of the study, oral and topical formulations of VISPO reduced hair fall by up to 29% (p< 0.001) and 22.19% (p< 0.01) from the baseline, respectively. Hair density increased by 5.17% and 7.61% in the oral and topical VISPO groups, respectively (p< 0.001). In addition, oral ingestion of VISPO resulted in a marked reduction in serum dihydrotestosterone (DHT) levels in the subjects compared to placebo (p< 0.001). However, the effect of the VISPO formulations on the anagen/telogen ratio was insignificant. No serious adverse effects were observed during the study.Conclusion: VISPO formulations reduced hair fall and promoted hair regrowth and scalp appearance in AGA patients. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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