Association between oral infections, triglyceride‐glucose index, and in‐stent restenosis.

Autor:	Wu, Yingle, Du, Laijing, Fan, Mengnan, Chen, Xinzhao, Tang, Yanyan, Wang, Yanyu, Wang, Ke, Wang, Shaoxin, Li, Guangping
Předmět:	BLOOD sugar analysis TRIGLYCERIDES STATISTICS RESEARCH CONFIDENCE intervals DRUG-eluting stents CROSS-sectional method MULTIPLE regression analysis PERIODONTAL disease ACUTE coronary syndrome SURGERY PATIENTS REGRESSION analysis CORONARY restenosis RISK assessment DESCRIPTIVE statistics RESEARCH funding STATISTICAL models STATISTICAL correlation ODDS ratio DISEASE risk factors DISEASE complications
Zdroj:	Oral Diseases; Nov2023, Vol. 29 Issue 8, p3698-3706, 9p
Abstrakt:	Objectives: To investigate oral infections in patients suffering in‐stent restenosis (ISR) and non‐ISR and analyze the possible correlation between the oral infection and triglyceride‐glucose (TyG) index, a clinical surrogate indicator of insulin resistance (IR). Materials and Methods: A cross‐sectional design was used, in which 586 patients with acute coronary syndrome who underwent coronary angiography 6–24 months after coronary stent implantation were recruited. The modified total dental index (TDI) was used to evaluate the status of oral inflammation. Results: In both univariate analyses, TDI scores [3 (1.5, 4.5) vs. 2.5 (1.5, 4.0), p < 0.01] and a multivariate regression model (OR = 1.202, 95% CI = 1.085–1.333, p < 0.01), the TDI significantly correlated with ISR. The TyG index was positively associated with ISR (OR = 1.766, 95% CI = 1.055–2.957, p < 0.05). Correlation analysis showed that TDI was positively correlated with TyG index (r = 0.190, p < 0.01). Using linear regression analysis, higher TDI scores were significantly associated with IR (95% CI = 0.029–0.063, p < 0.01). Conclusions: Oral infections and TyG index were independently and positively correlated with ISR in patients with acute coronary syndrome. Oral inflammatory burden assessed by TDI score was associated with IR. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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